San Francisco is the heart and soul of the startup world, with Silicone Valley being one of the first things to come to mind when you think of this ecosystem. With this in mind, it comes as zero surprise that there is a surplus of top startups in San Francisco and beyond. The ecosystem as a whole has a value of $677 Billion, which completely dwarves the global average of $10.5 Billion. Furthermore, the amount of funding that is received with each investment into the ecosystem also dwarves the global average, at least two times over.
We recently published our list of the Top San Francisco Startups To Watch in 2022.
1. Replicant
Year Founded: 2017
HQ: San Francisco, California
Size: 11–50
Founder(s): Andrew Abraham, Benjamin Gleitzman, Gadi Shamia
Replicant is a San Francisco startup that was founded in 2017 and is still currently based in the same city. The company provides AI-powered solutions for voice technology that makes the process of interacting with customers over the phone much easier. This minimizes mistakes and maximizes customer satisfaction. At the same time as this, the system also helps these same businesses to reduce their costs.
Since being founded four years ago, the company has done well to secure startup funding. The company has managed to secure deals with five investors, which in turn, has led the company to make a total of $35 Million in startup funding.
2. RapidAPI
Year Founded: 2015
HQ: San Francisco, California
Size: 101–250
Founder(s): Iddo Gino, Mickey Hasalvsky
RapidAPI is one of the most exciting startups in San Francisco, with the company being founded six years ago. The company provides a hub for APIs which allows developers to find the APIs that they need, manage them and connect them into their infrastructure. This helps developers to save a lot of time and create better solutions.
The startup has been very active in securing startup funding for growth and development. In total, the company has received funding from a total of 15 investors. The company has managed to raise a collective total of $122.5 Million in startup funding, with RapidAPI also taking over another company in that time.
3. Cribl
Year Founded: 2017
HQ: San Francisco, Califnornia
Size: 101–250
Founder(s): Clint Sharp, Dritan Bitincka, Ledion Bitincka
Cribl is a software startup in San Francisco, that was founded four years ago and has been going from strength to strength since then. The startup provides a solution to make big data simpler for businesses by allowing for the provision of a real-time data pipeline which also helps to simplify the process of log analytics.
Despite still being quite young, the company has managed to raise a significant amount of funding in its four years of trading. The startup itself has received investment from a pair of investors. These investors have pooled a total of $42.4 Million, which goes a long way to help with development and growth.
4. CapitvateIQ
Year Founded: 2017
HQ: San Francisco, California
Size: 101–250
Founder(s): Conway Teng, Hubert Wong, Mark Schopmeyer
CaptivateIQ is a California startup that was founded four years ago and is currently based in the city of San Francisco. The company provides a software solution that makes the process of conducting commission payments much easier. This is achieved through automation which prevents errors and also makes sure that commission is processed quickly so that salespeople can get paid.
The San Francisco startup has managed to raise a large amount of startup funding since it was founded four years ago. In total, the company has agreed to deals with seven investors. These seven investors have given the company a combined total of $62.6 Million.
5. InCountry
Year Founded: 2019
HQ: San Francisco, California
Size: 51–100
Founder(s): Peter Yared
InCountry is a data compliance startup that was founded two years ago and is currently based in the city of San Francisco. The company makes it easier to manage data compliance by ensuring that multinational companies can store, process and use data on their international employees, but in the same locality that they work and live in. This integration can be easily created in ten minutes.
The company has managed to make deals with a large number of investors since it was founded two years ago. In this short time, the company has managed to secure deals with 14 investors. These investments have led to the company raising a figure of $40 Million, a great figure to receive in two years.
6. Hevo Data
Year Founded: 2017
HQ: San Francisco, California
Size: 11–50
Founder(s): Manish Jethani, Sourabh Agarwal
Hevo Data is a San Francisco startup that was founded four years ago and is currently based in the city. The company has created unified platforms for data, which allows companies to understand the habits of their users and customers in a way that can be easily managed.
The company has seen investment from a total of seven investors since it was founded in 2017. These investors have managed to collectively pool a total of $13 Million into the company so that it can improve and develop further.
7. Afresh Technologies
Year Founded: 2017
HQ: San Francisco, California
Size: 11–50
Founder(s): Matt Schwartz, Nathan Fenner, Volodymyr Kuleshov
Afresh Technologies is a food and logistics startup that was founded four years ago and is currently based in San Francisco, California. The company provides an AI-powered solution that allows businesses to keep track of the level of demand for fresh items in grocery stores, as well as managing these items within the store.
Since the company was founded in 2017, it has managed to secure a large amount of startup funding over these years. In total, the startup has managed to strike deals with seven investors, which culminated in Afresh Technologies securing a total of $32.8 Million.
8. Secfi
Year Founded: 2017
HQ: San Francisco, California
Size: 51–100
Founder(s): Frederik Mijnhardt, Wouter Witvoet
Secfi is one of the premier up-and-coming startups in San Francisco, being founded four years ago. The startup itself collaborates with startup owners and employees to help them with their equity planning process and the creation of stock options financing. This helps employees to take real ownership of the businesses that they have helped to create.
Secfi has raised a gargantuan amount of startup funding in the short time that it has been trading. The startup struck deals with a total of 11 investors in this time and these investors have pledged a collective figure of $707 Million to the company to help it grow further.
9. Digbi Health
Year Founded: 2018
HQ: Mountain View, California
Size: 51–100
Founder(s): Ranjan Sinha
Digbi Health is a rapidly growing healthcare startup in California that was founded three years ago and is currently based in Mount View. The company has created a platform that takes the best of risk signals from genetics and gut microbiomes to help reverse the impact of certain illnesses like diabetes and inflammatory bowel conditions.
The company has received a good amount of startup funding in the three years that it has been trading, with the company managing to convince 8 investors to part with their money. This has allowed the business to raise a figure of $9.3 Million in startup funding in that short space of time.
10. MarketerHire
Year Founded: 2019
HQ: San Francisco, California
Size: 11–50
Founder(s): Chris Toy, Darren Litt, Raaja Nemani
MarketerHire is a San Francisco startup that was founded in 2019 and is currently still based in the city. The company helps other businesses to find the right marketing professionals to propel their business to new heights. This is achieved through pre-vetting of candidates and experts who hand-match the candidates with the companies that are looking to hire.
Despite only being founded two years ago, the company has managed to secure a good amount of startup funding. From a group of eleven investors, the California startup has managed to raise a figure of $4 Million to further develop its business model.
11. ArsenalBio
Year Founded: 2019
HQ: San Francisco, California
Size: 11–50
Founder(s): Sean Parker, W. Nicholas Haining
ArsenalBio is a San Francisco biotechnology startup that was founded two years ago. The company itself utilizes AI technology to assist in the treatment of cancer by creating programmable cell therapy treatment programs. The aim is to decrease costs and ultimately improve the outcome of patient care.
The mission and value of the company have attracted the attention of investors, with the company striking deals with seven investors. These investors have collectively put a total of $85 Million in the two short years that it has been trading.
12. CodePath
Year Founded: 2015
HQ: San Francisco, California
Size: 1–10
Founder(s): Jules Walter, Michael Ellison, Nathan Esquenazi, Timothy Lee
CodePath is an interesting entry on this list as the startup is a registered non-profit that was founded in 2015 and is aiming to improve computer literacy and access to programs to teach advanced computer science skills across a wide variety of colleges. So far, CodePath has entered into 30 educational institutions.
Despite the fact that the business is registered as a non-profit, this still hasn’t stopped it from receiving investment. From a single investor, CodePath has managed to secure an investment worth $1 Million.
13. Side
Year Founded: 2017
HQ: San Francisco, California
Size: 251–500
Founder(s): Edward Wu, Guy Gal, Hilary Saunders
Side is a real estate startup in San Francisco that was founded four years ago and has undergone rapid growth in that time. The company aims to improve real estate agencies and brokerages by improving the technological solutions that they use and provides a high-quality support network to ensure that they work to the best of their ability.
Side has managed to attract a huge amount of startup funding since it was founded in 2017. In total, the company has managed to agree to terms with 13 investors. These investors have helped the startup by providing a total of $263.5 Million.
14. Vouch Insurance
Year Founded: 2018
HQ: San Francisco, California
Size: 51–100
Founder(s): Sam Hodges, Travis Hedge
Vouch Insurance is a San Francisco startup that was founded in 2018 and is still operating from a headquarters in the city. The company creates tailored insurance services that are specifically made for other startups. Their platform allows businesses to manage risk, as well reducing the chances of that risk becoming a real problem in the future.
In the three years that the company has been trading, Vouch Insurance has managed to raise a figure of $94.2 Million to further the growth and development of the business. This investment was achieved from a large group of 16 investors.
15. CasaOne
Year Founded: 2017
HQ: Emeryville, California
Size: 101–250
Founder(s): Carlos Escutia, Madhusudan Kagwad, Shashank P S
CasaOne is a furniture startup that was founded four years ago and is currently based in Emeryville, California. The startup provides furniture rental services on a wide variety of home furnishings. There are also a variety of rent-to-buy options and 3D visualizations that help people to understand how the items will look in their homes.
The company has made a large amount of money from startup funding since it was founded in 2017. The company managed to strike deals with a total of eleven investors and these investors have pooled a total of $77.5 Million into the company to further its growth and development.
16. Noyo
Year Founded: 2017
HQ: San Francisco, California
Size: 11–50
Founder(s): Dennis Lee, Shannon Goggin
Noyo is a healthcare startup that was founded in 2017 and is currently based in San Francisco, California. The company provides a technology solution to improve the environment of health insurance. This is achieved through the use of APIs to facilitate the exchange of data for providers and customers.
Since the company was founded four years ago, it has managed to secure investment from a number of different sources. In total, eight investors decided to part with their money and back the company. This resulted in the company receiving a total of $12.5 Million in startup funding.
17. Fuzzy
Year Founded: 2016
HQ: San Francisco, California
Size: 11–50
Founder(s): Eric Palm, Zubin Bhettay
Fuzzy is a veterinary care startup that was founded five years ago and is currently based in San Francisco, California. The startup aims to make pet care more affordable and easy to access by connecting pet owners with vets through a telephony process. This allows for instant connection and medical help for your animals.
The company has managed to make a large amount of money from startup funding. A group of ten investors have put their support behind the company and this resulted in the business gaining $36.5 Million. Fuzzy has also acquired another business in the five years that it has been trading.
18. Capella Space
Year Founded: 2016
HQ: San Francisco, California
Size: 101–250
Founder(s): Payam Banazadeh, Uri Tintore, Will Woods
Capella Space is an aerospace technology startup that was founded in 2016 and is currently based in San Francisco. The company provides imaging technology using synthetic aperture radar to provide better images for both government agencies and commercial space flights.
Capella Space has received a large amount of startup funding to support its work. This was achieved through a group of 13 investors. These investors collectively put a total of $82 Million into the startup to improve its growth and development.
19. Voltus
Year Founded: 2016
HQ: San Francisco, California
Size: 101–250
Founder(s): Gregg Dixon, Matthew Plante
Voltus is an energy startup in California that is based in San Francisco and was founded in 2016. The company makes its money by selling cash-generating energy products to its customers. These customers exist in multiple industries.
The company has managed to secure a significant amount of investors since it was founded five years ago. In total, the business has secured investment from four investors that have collectively poured $66.1 Million into the business.
20. Siren
Year Founded: 2015
HQ: San Francisco, California
Size: 1–10
Founder(s): Henk Jan Scholten, Jie Fu, Ran Ma
Siren is a healthcare technology startup that was founded six years ago and is currently based in San Francisco, California. The company provides foot monitoring systems that help to detect and diagnose diabetes in patients. The devices monitor the temperature so that users can keep track of one of the biggest causes of diabetic foot ulcers.
The company has managed to secure investment from a variety of different sources. In total, the startup has managed to secure investment from 17 investors. These investors have put a total of $21.9 Million into Siren.
21. Pathstream
Year Founded: 2018
HQ: San Francisco, California
Size: 51–100
Founder(s): Eleanor Cooper
Pathstream is an educational startup that was founded in 2018 and is currently based in San Francisco, California. The company provides a platform that allows employees to learn technical skills that are currently in demand in the workplace.
The company has managed to secure a good amount of investment since it was founded three years ago. The startup has managed to secure investment from five sources and this has resulted in the company making a total of $13 Million.
